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IL-4 responses in the spleen cells of vaccinated mice in pDNA/HspX-PPE44-EsxV group, pDNA/HspX-PPE44-EsxV+BCG and control group (BCG, PBS and / or Vector). (a) P<0.001 compared to control group (PBS and/or Vector). (b) P <0.001 compared to positive and negative control groups (PBS, Vector, BCG). (c) P<0.001 compared to vaccine receiving groups (Prime-boost group). BCG: Bacillus Calmette–Guérin, IL-4: Interleukin-4
