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. 2020 Aug 1;9(3):561–572. doi: 10.1007/s40121-020-00325-2

Table 1.

Summary of in vitro EC50 values reported for hydroxychloroquine/chloroquine from selected studies

Author Medication Cell line MOI Time-pointa EC50b
Liu et al. [[35]] HCQ (chloroquine) VeroE6 0.01 48 h 4.51 (2.71)
0.02 4.06 (3.81)
0.2 17.31 (7.14)
0.8 12.96 (7.36)
Wang et al. [[36]] Chloroquine VeroE6 0.05 48 h 1.13
Yao et al. [[37]] HCQ (chloroquine) Veroc 0.01 24 h 6.14 (23.90)
48 h 0.72 (5.47)
Maisonnasse et al. [25] HCQ VeroE6 0.01 48 h 2.19d
72 h 4.39d

aPost-infection

bExpressed in µM

cNot stated in article if VeroE6 was the lineage utilized

dIC50 (not EC50)