Table 4.
Parameter | FTO (n = 300) | MC4R (n = 300) | ||||
---|---|---|---|---|---|---|
Genotype | Mean + SD | p value | Genotype | Mean + SD | p value | |
Age (years) | TT | 38.10 ± 8.68 | 0.108 | GG | 39.18 ± 9.02 | 0.945 |
TA/AA | 39.90 ± 10.04 | GA/AA | 39.10 ± 9.78 | |||
BMI (kg/m2) | TT | 27.42 ± 5.51 | 0.001* | GG | 28.53 ± 5.37 | 0.784 |
TA/AA | 29.57 ± 5.17 | GA/AA | 28.71 ± 5.45 | |||
FPI | TT | 9.26 ± 1.17 | 0.505 | GG | 9.50 ± 1.42 | 0.068 |
TA/AA | 9.36 ± 1.34 | GA/AA | 9.22 ± 1.17 | |||
FPG (mg/dl) | TT | 137.02 ± 31.18 | 0.963 | GG | 132.92 ± 23.43 | 0.140 |
TA/AA | 137.22 ± 40.20 | GA/AA | 139.44 ± 41.89 | |||
PPG (mg/dl) | TT | 201.25 ± 41.38 | 0.569 | GG | 198.44 ± 38.02 | 0.223 |
TA/AA | 204.56 ± 54.54 | GA/AA | 205.70 ± 54.36 | |||
HbA1c | TT | 6.79 ± 0.70 | 1.00 | GG | 6.71 ± 0.67 | 0.159 |
TA/AA | 6.79 ± 0.71 | GA/AA | 6.83 ± 0.72 | |||
Systolic BP (mmHg) | TT | 140.92 ± 19.86 | 0.074 | GG | 142.71 ± 19.34 | 0.735 |
TA/AA | 144.94 ± 18.25 | GA/AA | 143.49 ± 18.91 | |||
Diastolic BP (mmHg) | TT | 101.42 ± 14.78 | 0.627 | GG | 103.97 ± 16.90 | 0.095 |
TA/AA | 102.32 ± 16.31 | GA/AA | 100.81 ± 14.85 | |||
Cholesterol (mg/dl) | TT | 247.68 ± 15.87 | 0.762 | GG | 246.65 ± 15.23 | 0.248 |
TA/AA | 248.21 ± 13.90 | GA/AA | 248.71 ± 14.48 | |||
HDL (mg/dl) | TT | 44.98 ± 10.70 | 0.731 | GG | 46.02 ± 12.11 | 0.377 |
TA/AA | 45.44 ± 11.79 | GA/AA | 44.81 ± 10.87 | |||
LDL (mg/dl) | TT | 202.63 ± 17.46 | 0.383 | GG | 202.08 ± 21.43 | 0.257 |
TA/AA | 204.54 ± 19.32 | GA/AA | 204.62 ± 16.74 | |||
Triglycerides (mg/dl) | TT | 390.59 ± 81.47 | 0.333 | GG | 397.65 ± 88.64 | 0.062 |
TA/AA | 380.56 ± 92.16 | GA/AA | 377.89 ± 86.65 |
Significant at p < 0.05