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. 2020 Aug 1;11(9):2145–2157. doi: 10.1007/s13300-020-00896-w

Table 4.

Correlation of clinico-pathological parameters with polymorphisms (FTO and MC4R) using analysis of variance (ANOVA)-one-way ANOVA from summary data

Parameter FTO (n = 300) MC4R (n = 300)
Genotype Mean + SD p value Genotype Mean + SD p value
Age (years) TT 38.10 ± 8.68 0.108 GG 39.18 ± 9.02 0.945
TA/AA 39.90 ± 10.04 GA/AA 39.10 ± 9.78
BMI (kg/m2) TT 27.42 ± 5.51 0.001* GG 28.53 ± 5.37 0.784
TA/AA 29.57 ± 5.17 GA/AA 28.71 ± 5.45
FPI TT 9.26 ± 1.17 0.505 GG 9.50 ± 1.42 0.068
TA/AA 9.36 ± 1.34 GA/AA 9.22 ± 1.17
FPG (mg/dl) TT 137.02 ± 31.18 0.963 GG 132.92 ± 23.43 0.140
TA/AA 137.22 ± 40.20 GA/AA 139.44 ± 41.89
PPG (mg/dl) TT 201.25 ± 41.38 0.569 GG 198.44 ± 38.02 0.223
TA/AA 204.56 ± 54.54 GA/AA 205.70 ± 54.36
HbA1c TT 6.79 ± 0.70 1.00 GG 6.71 ± 0.67 0.159
TA/AA 6.79 ± 0.71 GA/AA 6.83 ± 0.72
Systolic BP (mmHg) TT 140.92 ± 19.86 0.074 GG 142.71 ± 19.34 0.735
TA/AA 144.94 ± 18.25 GA/AA 143.49 ± 18.91
Diastolic BP (mmHg) TT 101.42 ± 14.78 0.627 GG 103.97 ± 16.90 0.095
TA/AA 102.32 ± 16.31 GA/AA 100.81 ± 14.85
Cholesterol (mg/dl) TT 247.68 ± 15.87 0.762 GG 246.65 ± 15.23 0.248
TA/AA 248.21 ± 13.90 GA/AA 248.71 ± 14.48
HDL (mg/dl) TT 44.98 ± 10.70 0.731 GG 46.02 ± 12.11 0.377
TA/AA 45.44 ± 11.79 GA/AA 44.81 ± 10.87
LDL (mg/dl) TT 202.63 ± 17.46 0.383 GG 202.08 ± 21.43 0.257
TA/AA 204.54 ± 19.32 GA/AA 204.62 ± 16.74
Triglycerides (mg/dl) TT 390.59 ± 81.47 0.333 GG 397.65 ± 88.64 0.062
TA/AA 380.56 ± 92.16 GA/AA 377.89 ± 86.65

Significant at p < 0.05