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Inhibitory effect of XH against DNA single-strand breaks induced by menadione was examined using the comet assay. Hepa 1c1c7 mouse hepatoma cells were preincubated with XH for 48 h prior to menadione (10 μM) exposure for 30 min (■), or cells were treated with XH and menadione at the same time for 30 min (▴) before the comet assay was conducted. Each value is the average of triplicate measurements ± SD.
