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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Med Res Rev. 2018 Oct 11;39(2):749–770. doi: 10.1002/med.21540

Figure 7.

Figure 7.

Constraint diversification. (A)Upjohn Dihydroxylation of alkene gives dihydroxylated constraint. (B) Formal 1,3-dipolar cycloaddition reaction yields pyrazoline-constrained peptides.