Table 1.
Comparison of hormonal, antropometric, clinical, radiologic, biochemical and metabolic parameters between NFAI and ACS
| Variables | NFAI (N = 290) | ACS (N = 142) | P |
|---|---|---|---|
| Age (yr) | 61.76 ± 11.13 [62.67 (53.34–70.47)] | 64.90 ± 12.08 [66.1 (54.94–74.8)] | 0.008 |
| Maximal tumor size (mm) | 23.7 ± 11.1 [22.2 (16–29.0)] | 30.3 ± 13.3 [30 (22.5–35.5)] | < 0.001 |
| Size of rightsided tumor (mm) | 23.7 ± 9.8 [23 (17.3–28)] | 28.3 ± 11.1 [28.5 (20.0–35.0)] | < 0.001 |
| Size of leftsided tumor (mm) | 21.5 ± 11.9 [20 (14–25)] | 28.4 ± 15.5 [26 (20–35)] | < 0.001 |
| Basal serum cortisol (nmol/l) | 398.33 ± 128.24 [384 (320–451.8)] | 481.02 ± 240.00 [457 (350.25–556.25)] | < 0.001 |
| Serum cortisol after ODST (nmol/l)a | 32.8 ± 6.7 [29.4 (27.6–37.6)] | 108.6 ± 277.4 [67.8 (55.9–87.4)] | < 0.001 |
| ACTH (pmol/l) | 2.22 ± 1.42 [1.90 (1.17–2.81)] | 3.34 ± 7.54 [1.58 (1.11–2.58)] | 0.398 |
| Basal DHEAS (μmol/L) | 1.92 ± 1.29 [1.7 (1–2.43)] | 1.09 ± 0.94 [0.9 (0.4–1.4)] | < 0.001 |
| DHEAS after ODST (μmol/L) | 0.93 ± 0.76 [0.7 (0.4–1.2)] | 0.74 ± 0.67 [0.5 (0.3–1)] | 0.027 |
| Aldosteron (nmol/l) | 0.20 ± 0.13 [0.17 (0.11–0.25)] | 0.26 ± 0.21 [0.21 (0.12–0.3)] | 0.039 |
| Plasma Renin Activity – PRA (μg/l/h) | 1.25 ± 2.29 [0.38 (0.16–1.37)] | 1.68 ± 3.19 [0.59 (0.19–1.63)] | 0.132 |
| TSH (mE/l) | 2.93 ± 2.50 [1.68 (1.13–5.43)] | 2.75 ± 2.57 [1.41 (0.6–5.73)] | 0.186 |
| Body mass (kg) | 80.51 ± 15.92 [79.6 (68.75–89.45)] | 77.15 ± 16.37 [74.8 (65.78–87.18)] | 0.023 |
| BMI (kg/m2) | 29.33 ± 5.62 [28.59 (25.61–32.13)] | 28.56 ± 5.37 [27.77 (25.48–31.28)] | 0.287 |
|
Systolic blood pressure (mm Hg) |
138.36 ± 18.94 [140 (124–151)] | 141.63 ± 24.02 [140 (125–155)] | 0.339 |
|
Diastolic blood pressure (mm Hg) |
77.74 ± 11.51 [76 (70–85)] | 77.72 ± 12.02 [75 (70–85)] | 0.896 |
| Fasting glucose (mmol/liter) | 5.75 ± 1.40 [5.4 (4.9–6.13)] | 5.78 ± 1.71 [5.4 (5–6.1)] | 0.876 |
| Total cholesterol (mmol/liter) | 5.14 ± 1.14 [5.1 (4.4–5.8)] | 5.09 ± 1.17 [5.1 (4.3–5.75)] | 0.716 |
| HDL (mmol/liter) | 1.31 ± 0.36 [1.3 (1.1–1.5)] | 1.32 ± 0.41 [1.2 (1–1.5)] | 0.849 |
| LDL (mmol/liter) | 3.15 ± 0.98 [3.1 (2.4–3.78)] | 3.05 ± 1.00 [3 (2.5–3.7)] | 0.473 |
| Triglycerides (mmol/liter) | 1.75 ± 0.95 [1.5 (1.2–2.1)] | 1.77 ± 0.88 [1.6 (1.2–2.1)] | 0.622 |
afor 70 patients, data were provided as below 27.6, for 20 below 28 and for 1 below 31.3
Data are given as mean ± SD [Median (25–75%)]