Table 3.

Baseline and followup values for plasma cystatin C and creatinine

	Usual Care Group	NaCl Group	${\text{HCO}}_3^{-}$ Group	P Value
Plasma cystatin C, mg/dl
Year 0	1.04 (0.09)	1.04 (0.09)	1.05 (0.10)	0.90*
Year 10	1.33 (0.11)	1.34 (0.11)	1.24 (0.10)	<0.02*
P value†	<0.01	<0.01	<0.01
Plasma creatinine, mg/dl
Year 0	0.95 (0.08)	0.96 (0.08)	0.97 (0.07)	0.95*
Year 10	1.23 (0.08)	1.24 (0.08)	1.14 (0.07)	<0.01*
P value†	<0.01	<0.01	<0.01

Values are means (SD); n = 40 participants/group. Patients with chronic kidney disease stage 2 were divided into the following three groups: usual care or treatment with oral NaCl or NaHCO₃ (${\text{HCO}}_3^{-}$). P values at the end of the rows compare values in that row.

^*Kruskal-Wallis test for comparing three groups. All other P values were from one-way ANOVA.

^†P values below year 0 and year 10 values compare values for those years.