Table 7.
Baseline and followup plasma electrolytes and acid-base parameters
| Na+, meq/l | K+, meq/l | Cl−, meq/l | , meq/l | pH | Pco2, mmHg | Anion Gap, meq/l | |
|---|---|---|---|---|---|---|---|
| Usual care group | |||||||
| Year 0 | 139.3 (1.3) | 4.1 (0.3) | 103.1 (1.4) | 24.9 (0.6) | 7.405 (0.019) | 40.8 (0.2) | 11.3 (0.1) |
| Year 10 | 139.7 (1.4) | 4.2 (0.3) | 103.6 (1.4) | 23.9 (0.6) | 7.393 (0.020) | 40.3 (0.1) | 12.2 (0.1) |
| P value* | 0.32 | 0.79 | 0.21 | <0.01 | <0.01 | 0.04 | <0.01 |
| NaCl group | |||||||
| Year 0 | 139.1 (1.3) | 4.1 (0.2) | 103.3 (1.4) | 24.6 (0.5) | 7.403 (0.022) | 40.5 (0.1) | 11.2 (0.1) |
| Year 10 | 139.7 (1.3) | 4.1 (0.2) | 103.9 (1.4) | 23.7 (0.5) | 7.391 (0.021) | 40.1 (0.1) | 12.1 (0.1) |
| P value* | 0.25 | 0.96 | 0.22 | <0.01 | <0.01 | 0.03 | <0.01 |
| group | |||||||
| Year 0 | 139.2 (1.2) | 4.1 (0.2) | 103.2 (1.4) | 24.7 (0.6) | 7.404 (0.020) | 40.6 (0.1) | 11.3 (0.1) |
| Year 10 | 139.5 (1.2) | 4.0 (0.2) | 103.5 (1.4) | 24.8 (0.7) | 7.405 (0.020) | 40.7 (0.1) | 11.2 (0.1) |
| P value* | 0.95 | 0.047 | 0.78 | 0.62 | <0.01 | 0.46 | 0.54 |
Values are means (SD); n = 40 participants/group. Patients with chronic kidney disease stage 2 were divided into the following three groups: usual care or treatment with oral NaCl or NaHCO3 ().
*
P values were from a signed-rank test for assessing the within-group difference between baseline and year 10.