Table 1.

Data on the assay of chloroquine extemporaneous suspensions after filtration. The extemporaneous suspensions were obtained dispersing the crushed tablets in different aqueous vehicles (i.e., purified water, CMC, FOSP). An aqueous solution made of the pure drug substance was used as a control. The data are expressed as a mean percentage and relative standard deviation (RSD%) of three batches of suspension.

Vehicle	Filter	Drug assay (%)		RSD (%)
		4 mg/ml	25 mg/ml	4 mg/ml	25 mg/ml
Control	–	101.1	100.7	1.8	10.9
	0.2 µm, NYL	104.2	102.1	4.6	1.5
	0.2 µm, PES	101.4	99.6	1.7	1.3
	0.45 µm, PP	101.2	100.2	1.0	0.9
	0.45 µm, PTFE	101.5	99.7	3.1	0.9
Water	–	101.3	106.9	2.4	10.0
	0.2 µm, NYL	99.9	101.2	1.5	3.4
	0.2 µm, PES	100.4	102.1	2.1	3.4
	0.45 µm, PP	100.0	100.9	0.6	2.5
	0.45 µm, PTFE	100.0	99.3	0.7	0.3
CMC	–	108.0	114.0	7.3	6.4
	0.2 µm, NYL	102.4	103.7	0.9	1.0
	0.2 µm, PES	104.3	100.4	1.7	2.5
	0.45 µm, PP	104.4	105.5	1.7	3.7
	0.45 µm, PTFE	103.4	102.6	1.6	3.9
FOSP	–	97.7	103.7	2.1	7.1
	0.2 µm, NYL	105.4	103.3	2.4	5.8
	0.2 µm, PES	100.4	97.9	2.9	2.7
	0.45 µm, PP	99.7	99.0	3.9	2.2
	0.45 µm, PTFE	99.4	102.3	2.7	3.1