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Patients achieving success in ISGA with crisaborole in AD-301 and AD-302. Kaplan-Meier analysis shows that patients treated with crisaborole achieved the studies’ primary endpoint (of clear [0] or almost clear [1] and a ≥2-grade improvement from baseline on the ISGA) sooner than did those treated with vehicle ointment (P <.001). AD, Atopic dermatitis; ISGA, Investigator’s Static Global Assessment. (Reprinted from Paller et al with permission from Elsevier.54)
