Table 2.
Laboratory Findings of the Study Patients
| Median (IQR) | |||||
|---|---|---|---|---|---|
| Normal Range | Total (n = 111) | Pregnant (n = 31) | Nonpregnant (n = 80) | P Value | |
| Blood cell count | |||||
| White blood cell count, *109/L | 3.5–9.5 | 5.2 (3.8–7.2) | 6.9 (5.6–9.1) | 4.6 (3.5–6.1) | <.001 |
| Lymphocyte count, *109/L | 1.1–3.2 | 1.3 (1.0–1.7) | 1.1 (0.9–1.5) | 1.3 (1.1–1.8) | .113 |
| Lymphocyte, % | 20.0–50.0 | 28.4 (19.2–36.7) | 18.2 (12.4–23.9) | 31.8 (24.9–38.7) | <.001 |
| White blood cell count—lymphocyte count, *109/L | 0.3–8.4 | 3.6 (2.6–5.6) | 5.6 (4.1–8.0) | 3.2 (2.2–4.3) | <.001 |
| Neutrophil count, *109/L | 1.8–6.3 | 2.9 (2.0–4.8) | 5.2 (3.6–7.4) | 2.5 (1.7–3.3) | <.001 |
| Neutrophil, % | 50.0–70.0 | 61.8 (52.4–72.4) | 73.6 (68.5–81.9) | 56.6 (50.1–65.2) | <.001 |
| Platelet count, *109/L | 125–350 | 205 (158–255) | 180 (165–233) | 213 (157–257) | .414 |
| Hemoglobin, g/L | 115–150 | 125 (115–133) | 120 (112–130) | 127 (117–133) | .779 |
| Blood biochemical analysis | |||||
| C-reactive protein, mg/L | <10.0 | 2.5 (2.5–15.0) | 8.8 (2.5–33.4) | 2.5 (2.5–10.3) | .480 |
| Procalcitonin, ng/mL | <0.10 | 0.034 (0.023–0.056) | 0.068 (0.043–0.090) | 0.03 (0.01–0.04) | .715 |
| Sodium, mmol/L | 137–147 | 140 (139–144) | 140 (137–144) | 140 (139–143) | .610 |
| Potassium, mmol/L | 3.5–5.3 | 3.9 (3.6–4.2) | 3.9 (3.6–4.0) | 4.0 (93.6–4.3) | .086 |
| Chloride, mmol/L | 99–110 | 108 (105–109) | 107 (105–109) | 107 (105–109) | .324 |
| Albumin, g/L | 40–55 | 41 (37–43) | 37 (33–39) | 41 (39–43) | <.001 |
| Total bilirubin, μmol/L | 0–23 | 7.8 (6.0–10.3) | 8.4 (7.3–11.9) | 7.3 (5.6–9.4) | .624 |
| Alanine aminotransferase, U/L | 7–40 | 15.5 (10.8–22.0) | 15.5 (11.0–24.3) | 15.5 (10.0–20.8) | .411 |
| Aspartate aminotransferase, U/L | 13–35 | 19.5 (16.0–24.0) | 21.0 (16.0–25.8) | 19.0 (16.0–23.0) | .313 |
| Lactate dehydrogenase, U/L | 10–250 | 189 (160–223) | 200 (181–254) | 182 (152–218) | .311 |
| Blood urea nitrogen, mmol/L | 2.6–7.5 | 3.40 (2.76–4.03) | 3.02 (2.41–3.40) | 3.58 (2.94–4.28) | .138 |
| Creatinine, μmol/L | 41–73 | 47.5 (42.0–53.0) | 43.0 (37.3–49.8) | 50.0 (44.0–53.0) | .380 |
| Creatine kinase-MB, ng/mL | <5.00 | 0.58 (0.43–0.73) | 0.61 (0.35–1.12) | 0.54 (0.45–0.67) | .531 |
| Myohemoglobin, μg/L | 0–110 | 20 (14–28) | 16 (11–29) | 22 (16–28) | .356 |
| NT-pro B-type natriuretic peptide, pg/mL | 0–450 | 30 (17–62) | 45 (18–91) | 22 (12–47) | .268 |
| Prothrombin time, sec | 9.0–13.0 | 11.5 (11.0–12.0) | 11.0 (10.7–11.3) | 11.7 (11.2–12.4) | <.001 |
| Activated partial thromboplastin time, sec | 25.0–31.3 | 28.2 (26.2–30.3) | 27.8 (25.0–29.7) | 28.2 (26.5–30.4) | .332 |
| Fibrinogen, g/L | 2.00–4.00 | 3.64 (2.84–4.43) | 4.43 (3.99–5.12) | 3.10 (2.51–3.81) | <.001 |
| D-dimer, mg/L | 0.0–0.6 | 0.5 (0.2–1.4) | 1.8 (0.8–3.3) | 0.3 (0.2–0.5) | .015 |
| Fibrinogen degradation products, mg/L | 0.00–5.00 | 1.49 (0.56–4.57) | 5.15 (2.19–9.66) | 0.70 (0.37–1.56) | .211 |
| Antithrombin-3, % | 80.0–120.0 | 92.4 (82.6–99.9) | 92.9 (82.3–102.9) | 91.9 (83.1–97.6) | .329 |
| Cell immunity, *109/L | |||||
| CD3+ cell % | 56.0–86.0 | 74.9 (69.8–78.6) | 76.7 (73.5–80.0) | 73.7 (68.4–77.4) | .014 |
| CD3+ cell count | 723.0–2737.0 | 858.0 (704.8–1131.0) | 938.5 (741.5–1061.8) | 845.0 (635.8–1138.5) | .717 |
| CD4+ cell % | 33.0–58.0 | 40.3 (35.9–45.8) | 39.7 (35.3–41.5) | 41.1 (36.0–46.1) | .313 |
| CD4+ cell count | 404.0–1612.0 | 477.5 (341.8–640.8) | 463.0 (360.5–597.25) | 481.0 (325.3–653.3) | .606 |
| CD8+ cell % | 13.0–39.0 | 29.5 (23.8–34.2) | 32.3 (26.6–38.0) | 28.4 (22.3–32.4) | .003 |
| CD8+ cell count | 220.0–1129.0 | 357.5 (233.0–458.8) | 426.0 (344.3–465.3) | 329.0 (228.3–452.5) | .079 |
| CD4+/CD8+ ratio | 0.9–2.0 | 1.4 (1.1–1.8) | 1.2 (0.9–1.6) | 1.4 (1.1–2.0) | .023 |
| CD19+ cell % | 5.0–22.0 | 12.2 (9.5–15.0) | 10.3 (8.7–13.7) | 12.7 (9.9–16.5) | .091 |
| CD19+ cell count | 80.0–616.0 | 129.0 (96.3–185.5) | 127.5 (94.0–163.3) | 132.0 (96.5–209.0) | .324 |
| CD16+ CD56+ cell % | 5.0–26.0 | 11.1 (7.9–14.9) | 9.7 (7.8–14.8) | 11.2 (8.2–14.8) | .244 |
| CD16+ CD56+ cell count | 84.0–724.0 | 123.0 (81.3–171.8) | 123.0 (74.0–163.8) | 123.0 (85.8–171.8) | .361 |
| Humoral immunity, g/L | |||||
| IgG | 7.0–16.0 | 11.35 (10.10–12.88) | 9.76 (8.19–11.13) | 11.90 (10.90–13.50) | <.001 |
| IgM | 0.4–2.3 | 1.25 (0.91–1.56) | 1.08 (0.90–1.44) | 1.27 (0.92–1.71) | .170 |
| IgA | 0.7–4.0 | 2.01 (1.52–2.33) | 1.83 (1.45–2.18) | 2.05 (1.56–2.44) | .179 |
| IgE, IU/mL | <100.0 | 34.7 (9.15–118.5) | 29.9 (9.15–59.65) | 37.7 (99.2–125.8) | .174 |
| C3 | 0.9–1.8 | 1.0 (0.8–1.1) | 1.1 (1.0–1.2) | 0.9 (0.8–1.0) | <.001 |
| C4 | 0.1–0.4 | 0.2 (0.2–0.3) | 0.2 (0.2–0.4) | 0.2 (0.2–0.3) | .255 |
Abbreviation: IQR, interquartile range.