Mode/Frequency of administration |
Oral |
Daily |
2–3 times per week |
Weekly |
Subcutaneous |
2–3 times per week |
Weekly |
Fortnightly |
Monthly |
Intravenous |
Weekly |
Fortnightly |
Monthly |
Annual out-of-pocket costs (pounds) |
|
0 |
400 |
800 |
1200 |
1600 |
Average overall survival/Remission period |
1 year |
3 months |
9 months |
2 years |
6 months |
1 year 6 months |
3 years |
9 months |
2 years 3 months |
4 years |
1 year |
3 years |
5 years |
1 year 3 months |
3 years 9 months |
Mild-to-moderate side effects |
|
None |
Low risk (20%) – Duration (up to 2 months) |
Low risk (20%) – Duration (longer than 2 months) |
Med risk (40%) – Duration (up to 2 months) |
Med risk (40%) – Duration (longer than 2 months) |
High risk (60%) – Duration (up to 2 months) |
High risk (60%) – Duration (longer than 2 months) |
Severe side effects |
|
None |
Low risk (5%) – Duration (up to 2 months) |
Low risk (5%) – Duration (longer than 2 months) |
High risk (10%) – Duration (up to 2 months) |
High risk (10%) – Duration (longer than 2 months) |