Figure 5.
(A) Plasma concentrations of DTX versus time after intravenous (IV) administration of free DTX solution or DTX-loaded CLS-PEG NPs to rats at a dose of 10 mg/kg (mean ± SD, n = 6). (B) Plasma concentrations of DTX versus time after intratracheal (IT) administration of free DTX solution, freeze-dried or spray-dried CLS-PEG NPs loaded with DTX to rats at a dose of 10 mg/kg (mean ± SD, n = 6).
