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. 2020 Jul 28;15:5361–5376. doi: 10.2147/IJN.S249511

Figure 5.

Figure 5

(A) Plasma concentrations of DTX versus time after intravenous (IV) administration of free DTX solution or DTX-loaded CLS-PEG NPs to rats at a dose of 10 mg/kg (mean ± SD, n = 6). (B) Plasma concentrations of DTX versus time after intratracheal (IT) administration of free DTX solution, freeze-dried or spray-dried CLS-PEG NPs loaded with DTX to rats at a dose of 10 mg/kg (mean ± SD, n = 6).