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. 2020 Jul 31;10:12974. doi: 10.1038/s41598-020-69797-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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LE mice have decreased IL-17 cytokine production in the small intestine. (a) qRT-PCR of whole small intestine in NE, SE and LE mice demonstrated that LE mice had a significant decrease in IL-17A, TLR2 and TLR 4. (b) ELISA confirmed that LE mice had decreased production of IL-17A. The data shown are representative of 3 experiments with total of 6–10 mice in each group and analyzed with one-way ANOVA with post-hoc Tukey test. Data are depicted as mean ± SEM (*P < 0.05, **P < 0.01).