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. 2020 Jul 31;10:12920. doi: 10.1038/s41598-020-69715-3

Table 3.

Comparing the performances among models for predicting 2- and 5-year ESRD development in patients with CKD stages G3-G5 using IDI and NRI.

Models IDI (95% CI) P-value Continuous NRI (95% CI) P-value
2-year risk prediction
6-variable vs 8-variable − 0.016 (− 0.025, − 0.008) < 0.01 − 0.331 (− 0.364, − 0.272) < 0.01
4-variable vs 8-variable − 0.016 (− 0.024, − 0.010) < 0.01 − 0.330 (− 0.365, − 0.299) < 0.01
4-variable vs 6-variable 0.000 (− 0.001, 0.002) 0.81 − 0.186 (− 0.281, 0.182) 0.46
5-year risk prediction
6-variable vs 8-variable − 0.012 (− 0.019, − 0.006) < 0.01 − 0.317 (− 0.375, − 0.262) < 0.01
4-variable vs 8-variable − 0.011 (− 0.017, − 0.006) < 0.01 − 0.322 (− 0.367, − 0.272) < 0.01
4-variable vs 6-variable 0.000 (− 0.001, 0.001) 0.75 0.165 (− 0.067, 0.253) 0.24

ESRD end-stage renal disease, CKD chronic kidney disease, IDI Integrated Discrimination Index, NRI net reclassification improvement.