Table 5.
IDI and NRI (original vs recalibration) for predicting 2- and 5-year ESRD development in patients with CKD stages G3–G5.
| Model | IDI (95% CI) | P-value | Continuous NRI (95% CI) | P-value |
|---|---|---|---|---|
| 2-year risk prediction | ||||
| 8-variable | 0.025 (0.016, 0.035) | < 0.01 | 0.317 (0.294, 0.348) | < 0.01 |
| 6-variable | 0.019 (0.010, 0.027) | < 0.01 | 0.310 (0.284, 0.334) | < 0.01 |
| 4-variable | 0.017 (0.006, 0.025) | < 0.01 | 0.303 (0.272, 0.327) | < 0.01 |
| 5-year risk prediction | ||||
| 8-variable | 0.007 (0.003, 0.013) | < 0.01 | 0.155 (0.133, 0.185) | < 0.01 |
| 6-variable | − 0.010 (− 0.012, − 0.007) | < 0.01 | − 0.251 (− 0.282, − 0.222) | < 0.01 |
| 4-variable | − 0.007 (− 0.008, − 0.005) | < 0.01 | − 0.245 (− 0.272, − 0.217) | < 0.01 |
IDI Integrated Discrimination Index, NRI net reclassification improvement, ESRD end-stage renal disease, CKD chronic kidney disease.