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. 2020 Jul 31;3:412. doi: 10.1038/s42003-020-01148-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Phylogenetic trees of the 95 tet(X4)-positive E. coli isolates together with 287 publicly available draft genomes of tet(X4)-negative E. coli (PRJNA400107) from healthy humans across China (Neighbour-Joining trees constructed based on 166,544 core-genome SNPs). Red dots represent the 95 isolates positive for tet(X4). a An unrooted tree showing the four Bayesian lineages. b A circular tree showing the corresponding information and SNP differences between isolates that are positive or negative for tet(X4). Abbreviations: AH, Anhui; BJ, Beijing; FJ, Fujian; GS, Gansu; GD, Guangdong; GX, Guangxi; GZ, Guizhou; HI, Hainan; HB, Hubei; HUN, Hunan; HN, Henan; HL, Heilongjiang; JL, Jilin; JS, Jiangsu; JX, Jiangxi; LN, Liaoning; IM, Inner Mongolia; NX, Ningxia; QH, Qinghai; SD, Shandong; SX, Shanxi; SAX, Shaanxi; SH, Shanghai; SC, Sichuan; TJ, Tianjin; XZ, Xizang; XJ, Xinjiang; Yunnan; ZJ, Zhejiang.