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. 2020 Jul 31;10:12949. doi: 10.1038/s41598-020-67760-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The functional annotation of the 10-gene signature. (A) Ten representative KEGG pathway in high-risk and low-risk patients. (B) Functional annotation of the upregulated genes in high-risk patients with Metascape database. (C) Functional annotation of the downregulated genes in high-risk patients with Metascape database. Balls together with the same color indicates one biological process.