Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 31;11:3833. doi: 10.1038/s41467-020-17680-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — The results for overall breast cancer, oestrogen-receptor (ER)-positive breast cancer and ER-negative breast cancer are shown in Fig. 2a–c, respectively. The squares/dots represent the odds ratios (ORs) and the vertical lines represent the corresponding 95% confidence intervals, with middle quintile (40–60th) as the reference category. Solid lines represent the observed ORs, black dashed lines represent the predicted ORs of PRSs under a multiplicative polygenic model in the Asian population and the red dashed line represent the predicted OR in the European population. The analysis was conducted using 15,755 cases and 16,438 controls. Of 15,755 cases, 9989 were ER-positive breast cancer while 4611 were ER-negative breast cancer. Source data are provided in Supplementary Table 5.