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. 2020 Jul 31;11:3833. doi: 10.1038/s41467-020-17680-w

Fig. 4. Association between percentiles of 287-SNP polygenic risk scores and overall breast cancer risk in Chinese, Malay and Indian women from Malaysia and Singapore.

Fig. 4

Results were generated using 5236/5516 Chinese cases/controls, 1084/1332 Malay cases/controls and 580/1018 Indian cases/controls from Malaysia Breast Cancer Genetics (MyBrCa) and Singapore Breast Cancer Cohort (SGBCC) studies, stratified by ethnicity. The squares represent the odds ratios (ORs) and the vertical lines represent the corresponding 95% confidence intervals, with middle quintile (40–60th) as the reference category. Solid lines represent the observed ORs and dashed lines represent the predicted ORs of PRS under a multiplicative polygenic model. Source data are provided in Supplementary Table 6.