Table 5.
Absolute risk of developing overall breast cancer by percentiles.
| Chinese | Malay | Indian | |||||
|---|---|---|---|---|---|---|---|
| Percentile (%) | OR | Lifetime risk | Agea | Lifetime risk | Agea | Lifetime risk | Agea |
| <1 | 0.38 | 0.02 | NR | 0.02 | NR | 0.02 | NR |
| 1–5 | 0.48 | 0.03 | NR | 0.02 | NR | 0.02 | NR |
| 5–10 | 0.54 | 0.03 | NR | 0.03 | NR | 0.03 | NR |
| 10–20 | 0.67 | 0.04 | NR | 0.03 | NR | 0.03 | NR |
| 20–40 | 0.83 | 0.05 | NR | 0.04 | NR | 0.04 | NR |
| 40–60 | 1 | 0.06 | NR | 0.05 | NR | 0.05 | NR |
| 60–80 | 1.2 | 0.07 | NR | 0.06 | NR | 0.06 | NR |
| 80–90 | 1.51 | 0.09 | 44 | 0.08 | NR | 0.07 | NR |
| 90–95 | 1.82 | 0.11 | 40 | 0.09 | 43 | 0.09 | 46 |
| 95–99 | 2.22 | 0.13 | 37 | 0.11 | 38 | 0.11 | 31 |
| >99 | 2.72 | 0.16 | 35 | 0.13 | 35 | 0.13 | 39 |
Absolute risks were calculated based on self-declared ethnicity and ethnic-specific incidence and mortality data in Singapore and using 287-SNP PRS relative risk for overall breast cancer. NR never reached, i.e., the 10-year absolute risk in this percentile never exceed 2.3%.
aAge at which 10-year absolute risk exceeds 2.3%. The 2.3% threshold is the average 10-year absolute risk for a 50 years old woman of European ancestry (50 years old is the recommended age to begin regular mammographic screening Singapore).