Table 2.
Mediation analysis of Education Years on T2D, exploring seven T2D risk factors as mediators.
Mediator | Effect | Odds ratio (OR) | Lower 95% CI | Upper 95% CI | P value | Proportion mediated (%) 95% CI |
---|---|---|---|---|---|---|
Sibling with diabetes | 96 (58–134) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.97 | 0.64 | 1.46 | 8.67E−01 | ||
Mom with diabetes | 98 (59–137) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.98 | 0.59 | 1.64 | 9.45E−01 | ||
Dad with diabetes | 31 (19–43) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.52 | 0.30 | 0.91 | 2.11E−02 | ||
Being overweight | 42 (25–58) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.58 | 0.38 | 0.88 | 9.69E−03 | ||
HDL cholesterol | 27 (16–37) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.50 | 0.36 | 0.71 | 1.17E−04 | ||
High blood pressure | 10 (6–14) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.43 | 0.28 | 0.65 | 7.21E−05 | ||
Triglycerides levels | 13 (8–19) | |||||
Total | 0.39 | 0.26 | 0.58 | 3.89E−06 | ||
Direct | 0.44 | 0.30 | 0.66 | 5.82E−05 |