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. 2020 Jul 31;10:12908. doi: 10.1038/s41598-020-69114-8

Table 2.

Mediation analysis of Education Years on T2D, exploring seven T2D risk factors as mediators.

Mediator Effect Odds ratio (OR) Lower 95% CI Upper 95% CI P value Proportion mediated (%) 95% CI
Sibling with diabetes 96 (58–134)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.97 0.64 1.46 8.67E−01
Mom with diabetes 98 (59–137)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.98 0.59 1.64 9.45E−01
Dad with diabetes 31 (19–43)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.52 0.30 0.91 2.11E−02
Being overweight 42 (25–58)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.58 0.38 0.88 9.69E−03
HDL cholesterol 27 (16–37)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.50 0.36 0.71 1.17E−04
High blood pressure 10 (6–14)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.43 0.28 0.65 7.21E−05
Triglycerides levels 13 (8–19)
Total 0.39 0.26 0.58 3.89E−06
Direct 0.44 0.30 0.66 5.82E−05