Table 1.
In vitro Antiproliferative Activity of KA25 and KA26 Against Four Human Cell Lines (Three Colorectal Cancer Cell Lines and One Normal)
Cell Lines | KA25 | KA26 | ||||
---|---|---|---|---|---|---|
GI50 | TGI | IC50 | GI50 | TGI | IC50 | |
DLD-1 | 11.4±0.5 | 65±0.5 | >100 | 1.2±0.81 | >100 | >100 |
HT-29 | 1±0.3 | >100 | >100 | 2±0.76 | >100 | >100 |
LoVo | 8±0.76 | 13.8±0.52 | >100 | 15±0.8 | >100 | >100 |
MRC5 | 15±0.9 | >100 | >100 | 30±0.9 | >100 | >100 |
Abbreviations: IC50, Half maximal cytotoxic concentration; GI50, 50% growth inhibition; TGI, Total 100% growth inhibition.