Table 3:

Definitions used for recurrent UTI, UTI recurrence, and study follow up time

	Meta-analysis			Other Studies
Study	Domenici et al, 201631	Kranjcec et al, 20148	Porru et al, 201437	Genovese et al, 201738	Phe et al, 201732	Del Popolo et al, 201816	Efros et al, 201030	Marchiori et al, 201730
Definition of recurrent UTI used by each study
≥2 UTI/6 mo and/or ≥3 UTI/12 mo (Sx + Ucx)	•	•	•		•	•	•
≥2 UTI/12 mo (+ Ucx)				•
Not reported								•
Definition of incident UTI during study follow up
+Sx (no UCx, or not reported)	•
+ Sx and Ucx		•	•	•	•	•		•
Not reported/Not evaluated							•
Definition of study follow up time
16 weeks					•	•
6 months	•	•						•
24 weeks				•
12 months			•
Not reported/Not applicable							•

For all studies with UCx, definition of positive urine culture ranged from ≥10³ to ≥10⁵

Abbreviations: UTI, urinary tract infection; UCx, urine culture; Sx, lower urinary tract symptoms; mo, months