Table 2.
Cases clinical features.
| Case | MA | G | P | GA at delivery (weeks + days) | Days from COVID+ test to delivery | Maternal COVID-19 symptoms peripartum | Indication for delivery | Route of delivery | Birth outcome | Neonatal course | Fetal/Infant COVID test results |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MGH2 | 24 | 1 | 0 | 30 | 3 | Intubated/Ventilated | Twins NRFHT Maternal respiratory status |
CS | Livebirth X2 | Both twins to NICU with complications of prematurity | Each twin Negative X2 |
| MGH3 | 25 | 1 | 0 | 33 + 4 | PP day 5 negative | No symptoms | PPROM | VD | Livebirth | Benign | Negative X2 |
| MGH4 | 33 | 3 | 0 | 40 + 1 | 7 | Mild SOB, myalgias | Decreased fetal activity NRFHT |
CS | Livebirth | Benign | Negative X1 |
| MGH8 | 33 | 3 | 2 | 37 + 4 | 0 | No symptoms | Abruption, DIC required gravid Hysterectomy | CS | Livebirth | NICU for neonatal encephalopathy | Negative X1 |
| MGH9 | 32 | 2 | 0 | 36 | PP day 1 | Anosmia, fever, chills, fatigue | Placental previa, vaginal bleeding, labor | CS | Livebirth | Benign | Positive at 24 and 48 h of life |
| MGH10 | 37 | 5 | 3 | 22 | 7 | Fever, cough, head- ache | IUFD | VD | Stillbirth | Stillbirth | Not performed |
| MGH11 | 29 | 2 | 1 | 30 + 6 | 0 (H/O +test at 23 weeks GA then −test X2 but + on admission to LD) | Anosmia | Twins PPROM/PTL NRFHT 1 twin breech |
CS | Livebirth X2 | Both admitted to the NICU with respiratory complications related to prematurity | Each twin Negative X2 |
| MGH12 | 32 | 2 | 1 | 38 + 5 | 3 | No symptoms | Term labor | VD | Livebirth | Benign | Negative X1 |
| MGH13 | 25 | 4 | 2 | 36 + 3 | 3 | SOB, fever, cough, pneumonia on CXR | Maternal respiratory Status, NRFHT | CS | Livebirth | Benign | Negative X1 |
| MGH14 | 22 | 1 | 0 | 41 + 1 | 0 | No symptoms | Spontaneous labor | VD | Livebirth | Benign | Negative X1 |
| BWH2 | 25 | 2 | 1 | 39 + 5 | 3 | No symptoms | Spontaneous labor | VD | Livebirth | Benign | Negative X1 |
| BWH4 | 26 | 2 | 1 | 37 + 2 | 2 | Rhinorrhea, cough | Cholestasis | VD | Livebirth | Benign | Negative X1 |
| BWH5 | 39 | 4 | 3 | 37 + 1 | 0 | Fever, low oxygen saturation in labor | T2DM | CS | Livebirth | Macrosomia Benign |
Negative X1 |
| BWH6 | 33 | 1 | 0 | 38 + 3 | 0 | No symptoms | PIH, FGR | VD | Livebirth | Benign | Negative X1 |
| BWH9 | 35 | 4 | 0 | 38 + 3 | 3 | No symptoms | PET | CS | Livebirth | Benign | Negative X1 |
| BIDMC1 | 36 | 3 | 0 | 37.2 | 8 | DOE, cough | cHTN, GDM | CS | Livebirth | Benign | Not performed |
| BIDMC2 | 34 | 3 | 1 | 35.3 | 7 | Respiratory distress on 4 L O2 then intubated immediately PP, hypoxemia, cough | Maternal respiratory status, breech | CS | Livebirth | NICU for hypoglycemia and prematurity | Negative X1 |
| BIDMC3 | 28 | 2 | 1 | 31.6 | 9 | Fever, “worsening respiratory symptoms” no supplemental O2, cough, malaise, myalgia, rash | Maternal respiratory status | CS | Livebirth | NICU for respiratory distress, rash, and prematurity | Negative X1 |
| BIDMC4 | 42 | 2 | 0 | 29.3 | 1 | Fever, no respiratory symptoms | Chronic abruptio, PPROM, decreased fetal activity | VD | Livebirth | NICU for respiratory distress and prematurity | Negative X1 |
| BIDMC5 | 28 | 2 | 1 | 35.5 | 5 | Respiratory difficulty on 2 L O2, cough, fever, hemoptysis, sore throat, myalgia | Maternal COVID symptoms, Breech | CS | Livebirth | Mild pulmonary immaturity | Negative X1 |
cHTN chronic hypertension, CS cesarean section, CXR chest X-ray, DIC disseminated intravascular coagulation, DOE dyspnea on exertion, FGR fetal growth restriction, GDM gestational diabetes mellitus, H/O history of, HSV herpes simplex virus, IUFD intrauterine fetal demise, L liter, NRFHT nonreassuring fetal heart testing, PET preeclampsia, PIH pregnancy induced hypertension, PP post partum, PPROM preterm premature rupture of membranes, SOB shortness of breath, T2DM type 2 diabetes mellitus, VD vaginal delivery.