Table 1.
Laboratory findings of the index patient.
| Biochemical findings | Pre-HCTZ | Post-HCTZ | Reference values |
|---|---|---|---|
| Serum potassium | 6.3 | 4.00 | 3.5–5.3 mmol/L |
| Serum sodium | 142.8 | 138.9 | 137–147 mmol/L |
| Serum chlorine | 114.7 | 96.4 | 99–110 mmol/L |
| Serum creatinine | 60 | N/A | 37–110 μmol/L |
| eGFR | 122 | N/A | 56–122 mL/min/1.73 m2 |
| Arterial blood pH value | 7.286 | 7.400 | 7.35–7.45 |
| HCO3− | 17.6 | 26.2 | 22–27 mmol/L |
| PRA renin activity | 0.14 | 1.07 | 0.93–6.56 ng/mL/h |
| PRC aldosterone | 31.00 | 15.2 | 9.8–27.6 ng/dl |
| Serum cortisol (8 AM) | 300.2 | N/A | 147.3–609.3 nmol/L |
| Serum cortisol (4 PM) | 162.0 | N/A | 34–340 nmol/L |
| Serum cortisol (midnight) | 57.2 | N/A | <50 nmol/L |
| 24-h UFC | 43.61 | N/A | 20.3–127.6 μg/24 h |
| ACTH | 21.53 | N/A | 5.0–78 ng/L |
Note. eGFR: estimated glomerular filtration rate; ACTH: adrenocorticotropin; UFC: urinary free cortisol; HCO3−: serum bicarbonate; PRA: plasma renin activity; PRC: plasma aldosterone concentration; and HCTZ: hydrochlorothiazide.