Table 3.
Review of ongoing trials of coronary revascularization in severe aortic stenosis.
| Study acronym | Trial ID | Status | N | Description | Completion |
|---|---|---|---|---|---|
| FAVOR IV-QVAS | NCT03977129 | Recruiting | 792 | Randomized comparison of QFR and angiography-guided revascularization | 2022 |
| NOTION-3 | NCT03058627 | Recruiting | 452 | Routine FFR-guided complete revascularization with PCI compared with conservative management in TAVI patients | 2025 |
| FAITAVI | NCT03360591 | Recruiting | 320 | Comparison of angiography-guided versus physiology-guided PCI of patients with CAD undergoing TAVI | 2021 |
| TCW | NCT03424941 | Recruiting | 328 | FFR-guided PCI and TAVI in severe AS and multivessel CAD vs. CABG and SAVR | 2021 |
| FORTUNA | NCT03665389 | Not yet recruiting | 25 | Comparison of FFR derived from coronary computed tomography angiography before TAVR and FFR after TAVI | 2022 |
| None | NCT03442400 | Recruiting | 50 | Comparison of pre- and post-TAVI iFR/FFR values and assessment of short-term outcomes | 2019 |
| TAVI-PCI | NCT04310046 | Not yet recruiting | 980 | Comparison of FFR-guided PCI within 40 days before TAVI or within 40 days after TAVI | 2023 |