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. 2020 Jul 22;2020:8163789. doi: 10.1155/2020/8163789

Figure 2.

Figure 2

Lentiviruses were successfully transfected into neurons and reduced the expression of PPAR-γ; the neuroprotective effect induced by ta-VNS is reduced by PPAR-r silencing. (a) Fluorescent images of FLAG (green) in the right cortex 14 d after injection (scale bar = 100 μm). (b, c) Western blot images and statistical histogram of PPAR-γ expression with LV-siPPAR-γ injection 28 d after MCAO/R. ∗P < 0.05, compared to the I/R+LV-control group. (d, e) The mNSS and adhesive-removal somatosensory tests were performed before surgery and 14 and 28 d after MCAO/R (+P < 0.05 vs sham+LV-control group, ∗P < 0.05 vs I/R+LV-control group, and #P < 0.05 vs I/R+ta-VNS+LV-control group).