Table 1.
Baseline characteristics of the study population according to baseline serum uric acid quartile by sex.
| Baseline characteristics | SUA quartiles | P | |||
|---|---|---|---|---|---|
| Q1 (n = 10,058) | Q2 (n = 10,095) | Q3 (n = 10,021) | Q4 (n = 10,022) | ||
| Men | |||||
| SUA range (mg/dL) | ≤5.42 | 5.42-6.20 | 6.20-7.05 | >7.05 | |
| n | 5,282 | 5,333 | 5,296 | 5,295 | |
| Age (years) | 44.03 (12.83) | 42.9 (12.62) | 42.89 (12.91) | 42.59 (12.67) | <0.001 |
| Heart rate (beats/min) | 75.02 (9.9) | 75.21 (9.65) | 75.43 (9.72) | 76.35 (10.37) | <0.001 |
| BMI (kg/m2) | 24.78 (3.13) | 25.5 (3.13) | 26.22 (3.06) | 27.12 (3.16) | <0.001 |
| Height (cm) | 171.45 (5.76) | 172.06 (5.7) | 172.27 (5.77) | 172.51 (5.84) | <0.001 |
| Weight (kg) | 72.88 (10.19) | 75.58 (10.46) | 77.89 (10.37) | 80.82 (10.99) | <0.001 |
| WC (cm) | 86.21 (8.42) | 88.01 (8.53) | 89.82 (8.11) | 92.21 (8.35) | <0.001 |
| Blood pressure (mmHg) | |||||
| Systolic | 121.24 (15.21) | 121.54 (14.9) | 123.07 (14.57) | 124.54 (14.63) | <0.001 |
| Diastolic | 75.64 (10.25) | 76.59 (9.74) | 77.53 (9.95) | 79.19 (9.95) | <0.001 |
| SUA (mg/dL) | 4.81 (0.52) | 5.84 (0.22) | 6.63 (0.24) | 7.98 (0.79) | <0.001 |
| FPG (mmol/L) | 5.27 (0.52) | 5.28 (0.51) | 5.33 (0.51) | 5.37 (0.53) | <0.001 |
| TC (mmol/L) | 4.72 (0.87) | 4.81 (0.89) | 4.92 (0.91) | 5.08 (0.95) | <0.001 |
| TG (mmol/L) | 1.47 (1.15) | 1.67 (1.25) | 1.88 (1.37) | 2.32 (1.79) | <0.001 |
| HDL-C (mmol/L) | 1.32 (0.29) | 1.27 (0.27) | 1.24 (0.26) | 1.21 (0.26) | <0.001 |
| LDL-C (mmol/L) | 2.92 (0.72) | 2.99 (0.74) | 3.08 (0.73) | 3.15 (0.77) | <0.001 |
| eGFR (mL/min/1.73 m2) | 97.49 (19.05) | 93.96 (17.45) | 91.91 (16.81) | 88.94 (16.53) | <0.001 |
| White blood cell | |||||
| ALT (IU/L) | 20.00 (15.00-27.00) | 22.00 (16.80-30.10) | 23.40 (17.70-34.00) | 28.00 (19.93-40.10) | <0.001 |
| Women | |||||
| SUA range (mg/dL) | ≤3.77 | 3.77-4.37 | 4.37-5.05 | >5.05 | |
| n | 4,080 | 3,966 | 4,030 | 4,014 | |
| Age (years) | 37.79 (9.78) | 38.3 (10.71) | 39.67 (12.05) | 43.58 (14.04) | |
| Heart rate (beats/min) | 76.8 (9.9) | 76.63 (10) | 76.28 (9.75) | 76.02 (9.82) | <0.001 |
| BMI (kg/m2) | 22.28 (2.87) | 22.78 (3.09) | 23.46 (3.34) | 24.98 (3.72) | <0.001 |
| Height (cm) | 160.48 (5.23) | 160.82 (5.33) | 160.72 (5.37) | 160.22 (5.46) | <0.001 |
| Weight (kg) | 57.36 (7.74) | 58.9 (8.21) | 60.55 (8.8) | 64.08 (9.94) | <0.001 |
| WC (cm) | 72.68 (7.22) | 74.17 (7.7) | 75.85 (8.35) | 79.75 (9.19) | <0.001 |
| Blood pressure (mmHg) | |||||
| Systolic | 110.21 (14.02) | 110.77 (14.74) | 112.08 (15.06) | 116.89 (16.1) | <0.001 |
| Diastolic | 68.43 (9.05) | 69.41 (9.53) | 70.25 (9.65) | 73.16 (9.92) | <0.001 |
| SUA (mg/L) | 3.35 (0.35) | 4.09 (0.17) | 4.69 (0.19) | 5.78 (0.67) | <0.001 |
| FPG (mmol/L) | 5.01 (0.42) | 5.04 (0.44) | 5.08 (0.46) | 5.2 (0.52) | <0.001 |
| TC (mmol/L) | 4.5 (0.85) | 4.6 (0.87) | 4.75 (0.9) | 5.02 (0.97) | <0.001 |
| TG (mmol/L) | 0.94 (0.55) | 1.02 (0.65) | 1.13 (0.72) | 1.43 (0.92) | <0.001 |
| HDL-C (mmol/L) | 1.58 (0.34) | 1.55 (0.34) | 1.51 (0.33) | 1.44 (0.32) | <0.001 |
| LDL-C (mmol/L) | 2.6 (0.68) | 2.7 (0.7) | 2.82 (0.74) | 3.07 (0.79) | <0.001 |
| eGFR (mL/min/1.73 m2) | 113.28 (24.91) | 107.47 (23.54) | 103.33 (23.11) | 97.5 (22.36) | <0.001 |
| White blood cell | |||||
| ALT (IU/L) | 13.00 (10.08-16.90) | 13.20 (11.00-17.70) | 14.00 (11.00-19.00) | 17.00 (12.70-23.60) | <0.001 |
Abbreviations: BMI: body mass index; WC: waist circumference; SUA: serum uric acid; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; eGFR: estimated glomerular filtration rate; ALT: alanine aminotransferase. Data are mean (SD) and median (interquartile range). Quartiles 1-4: ≤5.44, >5.44~≤6.22, >6.22~≤7.08, and >7.08 mg/dL for men and ≤3.80, >3.77~≤4.38, >4.38~≤5.05, and >5.05 mg/dL for women.