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. 2020 Jul 23;2020:6538930. doi: 10.1155/2020/6538930

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Copyright © 2020 Hongming Su et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Andrographolide modulated gut microbiota composition. (a) Observed species, (b) Chao, (c) Ace, (d) Shannon's diversity, and (e) Simpson's diversity were obtained by analyzing 16S rDNA sequencing. (f) Statistical comparisons of gut bacterial profiles at the phylum level. (g, h) The Bacteroidetes/Firmicutes ratio was calculated. Control: db/db mice administered with vehicle; AG: db/db mice administered with 150 mg/kg andrographolide. Data represent means ± SEM (n = 6), ∗p < 0.05 versus the control group.