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Andrographolide improved the short-chain fatty acids (SCFAs) composition. (a) acetate, (b) propionic acid, (c) butyric acid, and (d) valeric acid were measured in fecal samples by gas chromatography (GC) in comparison with known standards. (e) Total SCFAs were the sum of each amount of individual fatty acids. Control: db/db mice administered with vehicle; AG: db/db mice administered with 150 mg/kg andrographolide. Data represent means ± SEM (n = 6), ∗p < 0.05 versus the control group.
