. 2020 Aug 2;161:1602–1617. doi: 10.1016/j.ijbiomac.2020.07.293

Table 1.

Current available templates in Protein Data Bank for zebrafish TLR and NLR model building.

Zebrafish	Uniprot ID	Template (PDB ID)	Description	Organism	Identity (%)
TLR1	B3DIW3	1FYV	TLR1	Human	57.52
TLR2	F1R1U3	5D3I	TLR 2	Mouse	34.03
TLR3	B8JIL3	3CIG	TLR3	Mouse	47.88
TLR4a^a	B3U3W0	3FXI	TLR4	Human	35.21
TLR5b^b	B3DIN1	3V44/3V47/5GY2	TLR5b	zebrafish	n/a
TLR6^c	Absent	n/a	n/a	n/a	n/a
TLR7	F1QY64	5GMF	TLR7	Rhesus macaque	56.79
TLR8a^a	F1R2P4	3W3G	TLR8	Human	41.66
TLR9	F1QY61	3WPB	TLR9	Horse	35.52
TLR10–13^c	Absent	n/a	n/a	n/a	n/a
TLR18^d	B3DKG5	3A79/3WPB	TLR6/TLR9	Mouse/Horse	~23
TLR19^d	A0A2R8Q6Z1	3J0A	TLR5	Human	~23
TLR20^d	F1QRG0	5ZSA	TLR7	Rhesus macaque	~23
TLR21	F1QMN8	4Z0C	TLR13	Mouse	30.52
TLR22	B3DJL6	3J0A	TLR5	Human	29.36
NOD1	X1WGQ4	5IRM/5IRL	NOD2	Rabbit	32.49
NOD2a^a	F8W3K2	5IRM/5IRL	NOD2	Rabbit	50.67

Represents TLR/NLR present in zebrafish with multiple copies (templates are shown for only one copy).

Crystal structure is available.

Represents a few TLRs absent in zebrafish, but are present in mouse/human.

TLRs with very low sequence identity (templates shown are based on the highest query coverage; whereas other TLR/NLR templates listed in the table are considered based on the maximum BLASTp score).