Table 2.

Historical milestone in clinical xenotransplantation attempted in human.

Year	Donor	Organ/tissue/cell	Patient Survival	Doctor	References
1667	Sheep	Bloods	survived	Jean Baptiste Denis	(Denis, 1667; Ekser et al., 2017)
1838	Pig	Cornea	several weeksa	Richard Kissam	(Hara and Cooper, 2011; Kissam, 1844)
1905	Rabbit	Kidney slice	16 days	Princeteau	(Lambrigts et al., 1998; Princeteau, 1905)
1906	Pig	Kidney	3 days	Mathieu Jaboulay	(Jaboulay, 1906; Lambrigts et al., 1998)
1963–1964	Chimpanzee	Kidneys	Up to 9 months	Keith Reemtsma	(Michel et al., 2015; Reemtsma et al., 1964)
1964	Gibbon	Cornea	>5 monthsc	Soomsawasdi B	Soomsawasdi et al. (1964)
1964	Chimpanzee	Heart	2 h	James Hardy	(Hardy et al., 1964; Michel et al., 2015)
1984	Baboon	Heart	20 days	Leonard Bailey	(Bailey et al., 1985; Michel et al., 2015)
1992	Baboon	Livers	70 days	Thomas Starzl	Starzl et al. (1993)
2013–2017	New born pig	Islets	NAb	Wei Wang	Wang et al. (2019)

^aIndicates graft survival.

^bNot available about the survival data (No death was reported). Substantial improvement of the condition was reported.

^c50% of the patients showed more than 5 months graft survival in 10 patients.