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. Author manuscript; available in PMC: 2020 Aug 2.
Published in final edited form as: Autism Res. 2020 Apr 21;13(6):998–1010. doi: 10.1002/aur.2303

Table 3.

Crude and Adjusted Associations (β and 95% Confidence Intervals) Between Parental Age and Offspring Social Communication Traits as Measured by Raw Total SRS Scores

N Crude Adjusteda Coadjustedb
Continuous models
 Maternal age (10 years) 223 1.17 (−8.40, 10.7) 2.16 (−7.69, 12.0) 2.70 (−9.60, 15.0)
 Paternal age (10 years) 223 0.42 (−6.78, 7.62) 0.63 (−6.62, 7.88) 0.08 (−8.82, 8.98)
Categorical models
 Maternal age categories
  <30 28 4.27 (−8.43, 17.0) 1.58 (−10.9, 14.1) 1.56 (−11.3, 14.4)
  30–34 (referent) 97 0.0 (referent) 0.0 (referent) 0.0 (referent)
  ≥35 98 2.40 (−6.07, 10.9) 2.02 (−6.50, 10.5) 2.04 (−7.45, 11.5)
 Paternal age categories
  <30 26 17.0 (3.61, 30.5) 10.7 (−3.00, 24.4) 11.0 (−2.92, 24.9)
  30–34 (referent) 70 0.0 (referent) 0.0 (referent) 0.0 (referent)
  35–39 79 7.89 (−1.70, 17.5) 5.76 (−3.92, 13.2) 5.47 (−4.51, 15.5)
  ≥40 48 7.76 (−3.19, 18.7) 5.15 (−5.84, 13.8) 4.31 (−8.65, 17.3)
 Combined effects
  Young parents 11 18.8 (0.57, 37.1) 16.1 (−1.84, 34.1)
  Referent 172 0.0 (referent) 0.0 (referent)
  Old parents 40 1.27 (−9.03, 11.6) 0.45 (−9.56, 10.5)

Note. Ns shown represent total n in analysis for continuous models, or n in that category for categorical models. Definitions as follows: young parents: both parents < 30 years; old parents: maternal age ≥ 35 and paternal age ≥ 40; referent combined effects category: all other combinations of parental age.

a

Adjusted for child’s sex, parental education, and parental race/ethnicity (maternal education and race/ethnicity used in maternal age and combined effects models; paternal education and race/ethnicity used in paternal age models).

b

Additionally adjusted for the other parent’s age. Combined effects models adjusted for maternal race and education, though estimates adjusting for paternal race and education instead were similar.