Figure 5.

The right eye of a patient suffering from neovascular AMD with doubt among the three retinal specialists as to the presence of subretinal fibrosis. (A) Fundus image; (B) OCT intensity image (colorscale: 0–33 dB); (C) cumulative retardation image (in rad); (D) local birefringence image (in deg/µm), where the speckled, highly fluctuating behavior (delineated with a solid red line) was attributed to depolarization due to stronger pigmentation; and (E) optic axis uniformity image. Scleral tissue is delineated with red dashed lines. High signal in OAxU is indicated by a black arrow. Despite the local birefringence showing significant signal, the scan was judged negative because neither OAxU nor cumulative birefringence supports the indication by local birefringence. The elevated birefringence in the lower right part on the scans signifies the sclera (which is also highly birefringent with a resulting high optic axis uniformity).