Table 1.

Baseline characteristics of subjects at risk of incident late AMD

	Subjects in Analysis* (n = 9066)
Characteristics	Non-cases (n = 8880)	Incident Cases† (n = 186)	P
Age, years, mean (SD)	65.4 (7.7)	70.3 (7.7)	<0.0001
Age, years (%)
55-65	58.0	26.9	<0.0001
65-75	28.4	45.1
75-85	11.9	24.2
85+	1.7	3.8
Gender (% male)§	42.4	41.4	0.740
Ethnicity (%)§	n = 7,897	n = 173
Caucasian	98.3	99.4	0.303
Body mass index, mean (SD)§	26.8	26.4	0.235
Hypertension (%)§	n = 8,791	n = 184
Present	59.1	59.2	0.054
Smoking (%)§	n = 8,802	n = 181
Present	22.1	24.1	0.033
Features at baseline (%)§
Drusen ≥63 µm	58.5	43.0	<0.0001
Drusen ≥125 µm	7.7	48.9
Drusen area in grid >10%	0.9	22.0
Hyperpigmentation	7.4	31.8
RPE degeneration	7.8	28.5

^*Subjects >55 years of age, with eye examinations, gradable fundus photos, no prevalent late AMD, and at least one follow-up visit.

^†Subjects with incident late AMD.

^§Sdjusted for age and sex.