Table 5.

Categorical Change of UACR before and after IVB (by Regression to the Mean)

Categorical Change of UACR		All Patients			Diabetic Patients
		Control	DM	P Value	NPDR	PDR	P Value
A1	Residual decrease	19 (51%)	13 (25%)	0.187	7 (27%)	6 (22%)	0.452
	Regression to the mean	14 (38%)	4 (8%)		3 (12%)	1 (4%)
A2	Residual decrease	3 (8%)	7 (13%)	0.237	5 (19%)	2 (7%)	0.085
	Regression to the mean	0	8 (15%)		2 (8%)	6 (22%)
	Residual increase	1 (3%)	5 (9%)		4 (15%)	1 (4%)
A3	Regression to the mean	0	3 (6%)	N/A	1 (4%)	2 (7%)	0.931
	Residual increase	0	13 (25%)		4 (15%)	9 (33%)
P value		0.006*	<0.001*		0.026*	<0.001*

Data are expressed as number (percentage). Categorical change of UACR by baseline categories is as follows: 1) for A1, residual decrease implied minor change or decreased of UACR ≥ 30%, and regression-to-the-mean implies increase of UACR ≥ 30%; 2) for A2, residual decrease implied decrease of UACR ≥ 30%, regression-to-the-mean implied minor change, and residual increase implied increase of UACR ≥ 30%; and 3) for A3, regression-to-the-mean implied decrease of UACR ≥ 30%, and residual increase implied increase of UACR ≥ 30% or minor change.

^*P value < 0.05 by χ² test.