Figure 1.

Protective effect of DB on liver histopathological alterations in APAP induced mice. (A) The chemical structure of Dipsacoside B (DB). (B) Serum ALT and AST levels in APAP-treated mice with or without DB were detected after APAP treatment for 4 h. (C) Survival rate of mice were pretreated with DB by intraperitoneal injection for 1 h before APAP induction. (D) Representative liver histopathology with hematoxylin/eosin staining of APAP-induced liver injury in mice, assessed by images capture (Scale bar=100 μm). n=6–8, *, P<0.05; **P<0.01; ***, P<0.005.