Figure 1.

Expected times, 10th, 25th, and 50th (percentile), from glomerular filtration rate (GFR)/proteinuria risk characterization (study baseline) to clinical composite event (50% GFR decline, renal replacement therapy [RRT], or GFR < 15 mL/min/1.73 m²), for 6 GFR/proteinuria risk stages, by chronic kidney disease (CKD) diagnosis. Estimated event times are generated from an accelerated failure time model using a conventional generalized gamma distribution with 7 beta indicator parameters: 6 risk stages (A-F) and glomerular CKD. Time to event is from baseline (time at which risk level was defined). Event is defined as RRT, GFR < 15 mL/min/1.73 m², or 50% GFR decline. (Reproduced from [11])