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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Magn Reson Med. 2020 May 9;84(5):2338–2351. doi: 10.1002/mrm.28306

Figure 2.

Figure 2.

Inversion recovery spectral editing of NAD(H). (A) Diagram of inversion-recovery (IR) pulse sequence. (B) Profile of the inversion band (U-shaped dashed line) over a brain 31P spectrum acquired with TR = 1.0 s using a pulse-acquire sequence without baseline correction. Note the baseline distortion and the signal overlap between NAD(H) and α-ATP. The inversion bandwidth covers α-ATP, NAD(H) and UDP(G). (C) Simulated inversion-recovery curves for the 31P Z-magnetizations of NAD(H) (red trace) and α- (blue) and β- (magenta) ATP. The simulation was based on steady-state Z-magnetization with 90° readout pulse and constant TR = 1.0 s. Abbreviations: ATP, adenosine triphosphate; NAD(H), nicotinamide adenine dinucleotide; PCr, phosphocreatine; PDE, phosphodiesters; PME, phosphomonoesters; and Pi, inorganic phosphate.