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. 2020 Jun 29;11(8):2196–2208. doi: 10.1111/1759-7714.13527

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© 2020 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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The effect of circ_0007385 knockdown on tumor growth in vivo. A549 cells were transfected with sh‐circ or sh‐NC, and then subcutaneously injected into the right flanks of nude mice (n = 5). (a) Tumor volume was measured every seven days after cell transplantation () sh‐NC, () sh‐circ. (b) Tumor weight was examined on day 28. (c and d) RT‐qPCR detected circ_0007385 and miR‐519d‐3p expression levels in tissues from neoplasm. (e) Western blotting evaluated HMGB1 protein expression level in tissues from neoplasm.

Inline graphic — The effect of circ_0007385 knockdown on tumor growth in vivo. A549 cells were transfected with sh‐circ or sh‐NC, and then subcutaneously injected into the right flanks of nude mice (n = 5). (a) Tumor volume was measured every seven days after cell transplantation () sh‐NC, () sh‐circ. (b) Tumor weight was examined on day 28. (c and d) RT‐qPCR detected circ_0007385 and miR‐519d‐3p expression levels in tissues from neoplasm. (e) Western blotting evaluated HMGB1 protein expression level in tissues from neoplasm.