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. 2020 Feb 4;47(10):2407–2416. doi: 10.1007/s00259-020-04683-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, b The upper panel (a) shows weighted correlation matrices based on SERT binding potential values (BP_ND) of PD patients and HC at baseline, as well as for the 10 PD patients with longitudinal data (the same 10 PD patients both at baseline and follow-up assessments for longitudinal analysis). The lower panel (b) shows brain modules at baseline and at follow-up. Brain modules I in blue, module II in orange. A anterior, P posterior, L left, R right, PD Parkinson’s disease, g. pallidus globus pallidus