Table 2. The correlation between S100A4 expression and clinicopathological features.
| Clinicopathological features | Number of studies | Number of patients | P-value | OR (95% CI) | Heterogeneity | Model | |
|---|---|---|---|---|---|---|---|
| I2 (%) | PHet | ||||||
| Gender | 17 | 1659 | 0.641 | 0.95 (0.75–1.19) | 0.0 | 0.623 | fixed |
| Age | 16 | 1612 | 0.010 | 0.67 (0.49–0.91) | 44.5 | 0.028 | random |
| Tumor size | 6 | 530 | 0.209 | 1.96 (0.69–5.62) | 84.2 | <0.001 | random |
| Differentiation | 14 | 1411 | <0.001 | 2.20 (1.69–2.85) | 34.7 | 0.098 | fixed |
| LNM | 20 | 1944 | <0.001 | 3.70 (2.25–6.06) | 79.3 | <0.001 | random |
| TNM stage | 17 | 1695 | <0.001 | 3.08 (2.10–4.53) | 56.6 | 0.002 | random |
| Smoking | 6 | 690 | 0.673 | 1.08 (0.76–1.52) | 38.9 | 0.146 | fixed |
| Pathological subtype | 14 | 1272 | 0.020 | 1.77 (1.09–2.88) | 67.2 | <0.001 | random |