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Serum tau levels and its correlation with MMSE and Receiver Operating Characteristic (ROC) curves. (A) Concentration of total-tau in serum samples in studied subjects. *p < 0.05, **p < 0.01 compared with age-matched healthy control group; ##p < 0.01 comparison with mild cognitive impaired group; n = sample size. (B) Correlation of tau concentration with MMSE scores. ROC analysis of serum tau proteins between (C) Control vs. moderate CI and (D) Control vs. severe CI groups.
