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. 2020 Jul 24;11:1547. doi: 10.3389/fmicb.2020.01547

FIGURE 1.

FIGURE 1

Distribution of emm types and multi-locus sequence type (ST) in invasive S. pyogenes isolates identified through the Active Bacterial Core surveillance in 2016 and 2017. (A) A bar plot of isolate count. Each bar represents an emm type and is colored according to ST. The green number under each bar indicates the most frequently observed ST (primary ST) within the emm type. The single, double, or triple-locus variants of the primary ST are indicated by SLV, DLV, and TLV, respectively. The magenta color indicates isolates differing from the primary ST by at least four of the seven loci used to define a ST. (B) Change in relative frequency of emm types between 2016 (open square) and 2017 (solid circle). The proportion of isolates belong to the emm type in all isolates of that year (n = 1,716 for year 2016 and 2,157 for year 2017) is shown. The vertical bars indicate an increase (red) or decrease (blue) in proportion. An asterisk (*) indicates the relative frequency of an emm type differed significantly between the 2 years (Fisher’s exact test, p < 0.00070). Only emm types containing 10 or more isolates are shown.