Table 2.
Clinical features and 11C-MET PET metrics based on IDH-genotype.
| PET Metric | All patients (n = 110) | IDH-mutant (n = 49) | IDH-wildtype (n = 61) | P-valuea |
|---|---|---|---|---|
| Age (mean ± SD) | 45.08 ± 13.56 | 42.63 ± 10.6 | 47.05 ± 15.35 | 0.090 |
| Age (≤ 45/>45 years) | 55/55 | 31/18 | 24/37 | 0.013 |
| Gender (M/F) | 67/43 | 27/22 | 40/21 | 0.263 |
| Midline Involvement (yes/no) | 37/73 | 2/47 | 35/26 | 0.000 |
| TNRmax | 1.7719 ± 0.3038 | 1.6692 ± 0.2474 | 1.8544 ± 0.3211 | 0.001 |
| TNRmean | 3.2421 ± 1.3193 | 2.8277 ± 1.1741 | 3.5749 ± 1.3440 | 0.002 |
| TNRpeak | 2.8114 ± 1.1222 | 2.4739 ± 0.9704 | 3.0824 ± 1.1690 | 0.004 |
| MTV | 48.6750 ± 54.9081 | 44.9551 ± 53.7083 | 51.6631 ± 56.1161 | 0.525 |
| TLMU | 87.9881 ± 104.0785 | 68.5628 ± 86.9409 | 103.5920 ± 114.3505 | 0.071 |
| SUVSD | 0.3783 ± 0.2819 | 0.2551 ± 0.1781 | 0.4772 ± 0.3108 | 0.000 |
a
comparison between IDH-mutant and IDH-wildtype.