TABLE 1.
Skin melanomas samples from the 10 NGS-based studies evaluated for the mutational and CNV frequency in the present report.
| Cutaneous melanomas | Acral melanoma | Total samples (N°) | Reference (PUBMED ID) | |||
| Primary | Metastatic | Primary | Metastatic | |||
| Berger MF, Nature 2012 | 0 | 25 | 0 | 0 | 25 | 22622578 |
| Snyder A, NEJM 2014 | 0 | 44 | 0 | 5 | 49 | 25409260 |
| Van Allen EM, Science 2015 | 0 | 92 | 0 | 0 | 92 | 26359337 |
| Hodis E, Cell 2012 | 15 | 85 | 2 | 3 | 100 | 22817889 |
| TCGA, PanCancer Atlas* | 0 | 363 | 0 | 0 | 363 | 26091043 |
| Krauthammer M, Nat Genet 2012 | 35 | 62 | 8 | 9 | 114 | 22842228 |
| Hayward NK, Nature 2017 | 54 | 86 | 14 | 21 | 175 | 28467829 |
| Kontogianni G, Cancers 2018 | 9 | 0 | 0 | 0 | 9 | 29596374 |
| Birkeland E, Nat Commun 2018 | 0 | 37 | 0 | 3 | 40 | 29991680 |
| Wilmott JS, Int J Cancer 2019 | 2 | 23 | 0 | 0 | 25 | 30178487 |
| Total samples (N°) | 100 | 822 | 24 | 41 | 992 | |
*Samples data from TCGA, PanCancer Atlas, were assessed by cBioportal repository (cBioPortal for Cancer Genomics, 2020).