Table 1.
Characteristics | Median (IQR)/Number (%) | P-value | ||
---|---|---|---|---|
Entire cohort | Training cohort | Validation cohort | ||
(N = 162) | (N = 108) | (N = 54) | ||
Age(year) | 58 (47–66.8) | 59 (47.2–72.5) | 58 (47–66) | 0.474 |
Sex | ||||
Male | 136 (83.9) | 91 (84.3) | 45 (83.3) | 1 |
Female | 26 (16.1) | 17 (15.7) | 9 (16.7) | |
Etiology | 0.076 | |||
HBV | 109 (67.3) | 78 (72.2) | 31 (57.4) | |
Others | 53 (32.7) | 30 (27.8) | 23 (42.6) | |
Tumor size (cm) | 7.5 (4.4–10.2) | 7.5 (4.2–11.1) | 7.4 (4.5–10) | 0.736 |
Tumor Number | ||||
1 | 95 (58.7) | 58 (53.6) | 37 (68.5) | 0.259 |
2 | 18 (11.1) | 14 (13.0) | 4 (7.4) | |
3 | 13 (8.0) | 11 (10.2) | 2 (3.7) | |
>3 | 36 (22.2) | 25 (23.2) | 11 (20.4) | |
BCLC stage | 0.775 | |||
A | 8 (4.9) | 5 (4.6) | 3 (5.6) | |
B | 154 (95.1) | 103 (95.4) | 51 (94.4) | |
ALBI grade | 0.894 | |||
A | 65 (40.1) | 42 (38.9) | 23 (42.6) | |
B | 93 (57.4) | 63 (58.3) | 30 (55.6) | |
C | 4 (2.5) | 3 (2.8) | 1 (1.8) | |
Child-Pugh class | 1 | |||
A | 140 (86.4) | 93 (86.1) | 47 (87.0) | |
B | 22 (13.6) | 15 (13.9) | 7 (13.0) | |
AFP (ng/ml) | 0.127 | |||
<400 | 64 (39.5) | 38 (35.2) | 26 (48.2) | |
≥400 | 98 (60.5) | 70 (64.8) | 28 (51.8) | |
AST (U/L) | 47.8 (31–70.5) | 44.5 (34.1–68.6) | 49.5 (30.8–75.2) | 0.568 |
ALT (U/L) | 39 (26.2–59) | 34.5 (24.2–56.4) | 41 (27–59) | 0.552 |
Prothrombin time (s) | 12.5 (11.7–13.9) | 12.2 (11.8–13.3) | 12.6 (11.7–14) | 0.337 |
Albumin (g/L) | 39 (35.8–43) | 39.1 (35–41.9) | 39 (36–43.4) | 0.534 |
Total bilirubin (μmol/L) | 19.6 (12.4–22.9) | 15.9 (10.3–21.6) | 19.9 (13.2–25.2) | 0.094 |
IQR, interquartile range; HBV, hepatitis B virus; BCLC, Barcelona Clinic Liver Cancer; ABLI, albumin-bilirubin; AFP, alpha-fetoprotein; AST, aspartate transaminase; ALT, alanine transaminase.
Median (IQR) are shown for continuous variables, whereas numbers (%) are shown for categorical variables.
P-values were calculated by the Mann-Whitney U-test for the continuous variables and the Fisher exact test for the categorical variables.