Skip to main content
. 2020 Jul 21;10:1196. doi: 10.3389/fonc.2020.01196

Table 1.

Characteristics of patients in the training and validation cohorts.

Characteristics Median (IQR)/Number (%) P-value
Entire cohort Training cohort Validation cohort
(N = 162) (N = 108) (N = 54)
Age(year) 58 (47–66.8) 59 (47.2–72.5) 58 (47–66) 0.474
Sex
Male 136 (83.9) 91 (84.3) 45 (83.3) 1
Female 26 (16.1) 17 (15.7) 9 (16.7)
Etiology 0.076
HBV 109 (67.3) 78 (72.2) 31 (57.4)
Others 53 (32.7) 30 (27.8) 23 (42.6)
Tumor size (cm) 7.5 (4.4–10.2) 7.5 (4.2–11.1) 7.4 (4.5–10) 0.736
Tumor Number
1 95 (58.7) 58 (53.6) 37 (68.5) 0.259
2 18 (11.1) 14 (13.0) 4 (7.4)
3 13 (8.0) 11 (10.2) 2 (3.7)
>3 36 (22.2) 25 (23.2) 11 (20.4)
BCLC stage 0.775
A 8 (4.9) 5 (4.6) 3 (5.6)
B 154 (95.1) 103 (95.4) 51 (94.4)
ALBI grade 0.894
A 65 (40.1) 42 (38.9) 23 (42.6)
B 93 (57.4) 63 (58.3) 30 (55.6)
C 4 (2.5) 3 (2.8) 1 (1.8)
Child-Pugh class 1
A 140 (86.4) 93 (86.1) 47 (87.0)
B 22 (13.6) 15 (13.9) 7 (13.0)
AFP (ng/ml) 0.127
<400 64 (39.5) 38 (35.2) 26 (48.2)
≥400 98 (60.5) 70 (64.8) 28 (51.8)
AST (U/L) 47.8 (31–70.5) 44.5 (34.1–68.6) 49.5 (30.8–75.2) 0.568
ALT (U/L) 39 (26.2–59) 34.5 (24.2–56.4) 41 (27–59) 0.552
Prothrombin time (s) 12.5 (11.7–13.9) 12.2 (11.8–13.3) 12.6 (11.7–14) 0.337
Albumin (g/L) 39 (35.8–43) 39.1 (35–41.9) 39 (36–43.4) 0.534
Total bilirubin (μmol/L) 19.6 (12.4–22.9) 15.9 (10.3–21.6) 19.9 (13.2–25.2) 0.094

IQR, interquartile range; HBV, hepatitis B virus; BCLC, Barcelona Clinic Liver Cancer; ABLI, albumin-bilirubin; AFP, alpha-fetoprotein; AST, aspartate transaminase; ALT, alanine transaminase.

Median (IQR) are shown for continuous variables, whereas numbers (%) are shown for categorical variables.

P-values were calculated by the Mann-Whitney U-test for the continuous variables and the Fisher exact test for the categorical variables.